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Heliyon 10, e36659

Regarding ferroptosis regulation, GGT-activated extracellular GSH catabolism produces iron-derived ROS, inducing lipid peroxidation via NF-B pathway activation (112)

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Concomitantly, HSV-1 reactivation from its latent phase was demonstrated by the detection of viral ICP4 protein in the TG and cerebral cortex of mice 60 days post-infection, and was accompanied by the up-regulation of markers of neuroinflammation, such as TLR4, IFN /, and phosphorylated IRF3 (p-IRF3

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