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In mice, GHK-Cu protected lung tissue from acute lung injury (ALI) by suppressing inflammatory cell infiltration and increasing antioxidant enzyme activity

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All solutions were administered to the rats through Acrodisk filters

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1 and 2 receptors are G s coupled therefore antagonism of their activation reduces activity of adenylyl cyclase and its downstream signalling via cyclic adenosime monophosphate and protein kinase A (PKA)