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Absolute contraindications to GLP-1 receptor agonists include: Personal history of medullary thyroid carcinoma Family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Pregnancy (for weight management indications) Severe gastrointestinal disease, including gastroparesis Patients should be specifically questioned about these conditions during pre-treatment evaluation

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Existing evidence suggests that GLP-1RAs may influence binge-eating symptoms and eating-disorder-related psychopathology, but the effects are heterogeneous and depend strongly on study design, behavioural context, and patient phenotype

Without training, youll lose muscle along with fat

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