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Xiao, J

Bertola A, Mathews S, Ki SH, Wang H, Gao B

The median dosing period per prescription was 5 days (interquartile range: 312 days)

A light-responsive hydrogel of cyclo-nitrobenzene-modified hyaluronic acid was designed to bind firmly to intraoral wound tissue within seconds of light exposure and was adherent for more than 24 h (Zhang et al., 2021b)

Without DAC (Mod GRF 1-29), the half-life is around 30 minutes, requiring more frequent dosing but preserving the natural pulsatile GH release pattern