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Semaglutide may influence the metabolism of SSRIs through the cytochrome P450 enzyme system via the CYP2C19 and CYP2D6 subtypes
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320 , H2080H2100 (2021)
Careful supervision and personalized regimens are advised to optimize outcomes and maintain safety with retatrutide treatment
A clinical study involving 564 adults (BMI 30-40 kg/m2, without T2DM) found that compared with orlistat (3120 mg, weight loss of 4.1 kg), LIR (subcutaneous administration of 1.2 mg/d, 1.8 mg/d, 2.4 mg/d or 3 mg/d) had an average weight loss of 4.8-7.2 kg, the two-year extended experiment of which also showed similar results (88, 89)
It is the most widely used drug for the treatment of diabetes for people who cannot control their blood sugar through diet and exercise
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