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PM stimulation of dendritic cells (DCs) from Nrf2 / mice enhances oxidative stress and inflammatory cytokine production and suppresses antioxidant induction (74), indicating that Nrf2 has important roles in antioxidative stress and proallergic Th2-mediated immunity orchestrated by DCs
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Although no physiological or outcome-based claims can be made, the molecule continues to appear in: Enzymatic pathway discussions Cell-signalling research Methyltransferase-related studies Computational modelling of enzyme interactions Small-molecule inhibitor development Because NNMT has been referenced in scientific settings involving metabolic process mapping and cellular signalling, synthetic analogues such as 5-Amino-1MQ remain relevant within modern biochemical interest
Leung1 , Pang Zhang1,2, Jenny K.W
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