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Oxidative stress can contribute to fatigue and low energy levels

lets look at the cellular biology and biochemistry: Glutathione plays a role in many cellular functions including cell growth and repair, DNA synthesis and repair, metabolism of toxins, carcinogens and xenobiotics, and the conjugation of heavy metals

Distinct classes of complex structural variation uncovered across thousands of cancer genome graphs

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Int Urogynecol J 2017

These cells appear to contribute to the aging process and age-related diseases through the senescence-associated secretory phenotype (SASP), which fosters a pro-inflammatory environment detrimental to tissue function and integrity