The enzyme beta-secretase cleaves APP to produce A peptides, particularly A42, which aggregate into toxic oligomers that form plaques
The peptide mimics endogenous alpha-MSH but with improved stability and receptor selectivity
Retrieved June 21, 2022,from 2 Lenzi A, Lombardo F, Gandini L & Dondero F
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Functionally, peptides are signal modulators
It is more often discussed as a repair-focused compound because of its proposed effects on inflammation, tissue healing, angiogenesis, and mucosal protection