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Heart Outcomes Prevention Evaluation (HOPE) Study Investigators, 2000
Glucagon-like peptide 1 and atrial natriuretic peptide in a female mouse model of obstructive pulmonary disease
Stangier J, Rathgen K, Sthle H, Mazur D
GLP-1Rs are expressed in the pancreas, intestinal intraepithelial lymphocytes, myocardium, adipose tissue, kidney, liver, blood vessels, lungs and in the CNS.2,3 Although GLP-1 is known for its incretin effect, which it shares with glucose-dependent insulinotropic peptide (GIP), the intake-regulating action, essential for its efficacy against obesity, occurs through its interaction with receptors located in the CNS.1,5 The GLP-1 peptide can reach the central nervous system (CNS) via peripheral vagal afferents, which transmit its action through the nodose ganglion to the nucleus tactus solitarius (NTS)
These medications may even help protect the retina
Viollet, B., Kahn, A
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