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Peters, MD, CDE, professor and clinical scholar, Keck School of Medicine of the University of Southern California, and director, agreed that in the simplest terms, a plateau occurs because the body becomes more and more used to the weight loss intervention

In clinical trials for weight management (SURMOUNT-1), participants without diabetes lost approximately 15% of body weight at 5 mg, 20% at 10 mg, and 21% at 15 mg over 72 weeks

While this might seem salvageable, there's no way to verify remaining potency at home, and administering a partially degraded solution wastes both the injection and the therapeutic window

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