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Glutathione, as a major intracellular antioxidant, maintains oxidative stress balance, decreases inflammatory responses, and apparently promotes periodontal inflammation indicators, dispalying impvital ortant potential for clinical application

A change in GSH and GSSG levels are important when assessing toxicological responses and an indicator of oxidative stress, potentially leading to apoptosis or cell death

GHK-Cu differs from other signal peptides (Matrixyl, acetyl hexapeptide-8, palmitoyl tripeptides) in its copper-coordinated mechanism and broad gene-expression effects

Additionally, the glutathione peroxidases play a critical role in thyroid function because they catalyze the degradation of peroxides generated during thyroid hormone synthesis (10)

GSH and GSSG Quantification : Accurate measurement of reduced and oxidized glutathione levels to assess cellular redox status

Dudka, J