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Studied in research involving extracellular matrix remodeling, collagen synthesis, and metalloproteinase signaling

Disorders of metabotropic glutamate (mGlu) receptors and neurotrophins have significant negative effects on neuroplasticity, leading to depression, but LAC regulate brain type 2 metabotropic glutamate (mGlu2) receptors and N-methyl-D-aspartic acid (NMDA) receptors to induce antidepressant effect (8385)

RNA concentrations were measured by nanodrop and cDNA was constructed using the REVERTAID H MINUS cDNA kit (Thermo Scientific, Leiden, The Netherlands)

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