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Mechanisms of leptin action and leptin resistance

Its about something almost no one in rheumatology is publicly discussing yet microdosing GLP-1 medications for psoriatic arthritis

And then there is the potential for side effects

When GLP-1 activates these brain regions, two things happen: You feel full and satisfied, and naturally stop wanting to eat more High-calorie, high-sugar foods feel less appealing the craving for them is turned down A 2014 study used brain scans (fMRI) to show this happening in real time in human volunteers GLP-1 receptor activation actually reduced brain activity in the regions that process hunger and food rewards

Those whove tried oral supplements without experiencing symptom improvement should consider injection therapy

Do not stop the medication cold turkey, as it may cause your blood sugar to increase