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This enrolled 390 people with type 2 diabetes, all on insulin, and randomised them to metformin 850 mg three times daily or placebo, with a follow-up of just over 4 years (de Jager et al, 2010)
doi:10.1007/978-1-4419-7104-3_4
Deficiency is common in those with fatigue, brain fog, or nutrient absorption issues, especially individuals with gastrointestinal conditions, vegans and vegetarians, or those taking medications like metformin or proton-pump inhibitors
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What are the primary causes of vitamin B12 deficiency
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