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Hypothemycin, one of the resorcylic acid lactones, is a representative inhibitor targeting cysteine residues located in the ATP site of Ser/Thr/Tyr protein kinases

J Pharmacol Exp Ther 298(2):403410 Ethics declarations Ethical approval The patients in this manuscript have given written informed consent to the publication of their case details

We will present the prognostic value for survival of baseline (i.e., diagnostic workup) patients self-reported fatigue (by the EORTC QLQ-C30) in a sample of 902 patients with MDS enrolled in an international study

Epithalon Side Effects Epithalon has a favorable safety profile with no major side effects having been associated with long-term administration of the peptide

Caffeine is acidic and relaxes the esophageal sphincter, which can worsen acid reflux