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Lau and colleagues (J Med Chem, 2015) published the foundational discovery paper describing the systematic optimisation that led to semaglutide

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in 2025, the European Medicines Agency concluded that NAION is a very rare side effect of semaglutide medicines

Semaglutide Hype or Hope: Evidence-based Review in Diabesity

Tirzepatide (as Mounjaro) shows superior A1C reduction