compared the effects of cotadutide (a dual GLP-1/GCG receptor agonist), liraglutide, and obeticholic acid in two mouse models of NAFLD [amylin liver NASH (AMLN) diet mice and AMLN diet ob/ob mice] to show that cotadutide outperformed other treatments in improving major histological endpoints, i.e., hepatic steatosis, inflammation, NAS, and fibrosis
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We found a significant decrease of the number of hospitalizations for vomiting after treatment (median [IQR]): 0.50 [3] (before treatment) vs
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Researchers also dont know to what extent GSH supplements influence these outcomes over time and what dosage and type of supplements may be best for different conditions