The authors concluded, Tirzepatide treatment led to similar improvements in HbA1c, body weight and cardiometabolic markers, irrespective of age at T2D [type 2 diabetes] diagnosis
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So just like patients using tirzepatide for obesity, theyll start low and go slow
These findings highlight the need for prospective studies that integrate longitudinal assessments of weight, thyroid function, and levothyroxine dosing to validate these results and clarify the mechanisms linking GLP-1RA use to cardiovascular outcomes, including atrial fibrillation/flutter and stroke
Scientists suggested that environmental and genetic risk factors, exposure to chemical pollutants, heavy metals, mycotoxins, lifestyle, age, infections, cardiovascular dysfunctions, T2D, cellular senescence, and head injuries may play a critical role in pathogenesis of AD (232, 236238)
Some patients successfully maintain with lower doses, spacing injections, or transitioning off medication after 2-3 years if they've built sustainable habits and addressed underlying metabolic dysfunction