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[7] In practice, some protocols use 1 mg IM monthly for maintenance once levels are stabilized

B12 supplements may reduce fatigue and improve endurance, making them popular among athletes and individuals with busy lifestyles

Some people experience digestive upset from high-dose B12 supplements

While effective in supplementing B12 levels, they are not derived from natural food sources and are formulated to mimic the active forms of B12 found in the body

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If you are severely deficient in vitamin B12, you might be recommended B12 shots every other day for about two weeks to replenish your B12 stores and correct symptoms