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This synthetic 43-amino-acid peptide derives from thymosin beta-4, one of the most abundant intracellular proteins in mammalian cells

The progressive neurodegenerative illness amyotrophic lateral sclerosis (ALS) damages motor neurons in the brain and spinal cord, resulting in muscle weakening and atrophy (Zarei et al., 2015)

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Noncanonical Roles of Caspase-4 and Caspase-5 in Heme-Driven IL-1 Release and Cell Death