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Additionally, he reported paresthesia predominantly affecting the right thumb and persistent neck pain exacerbated by forward bending
Moreover, UA-induced inflammation and oxidative stress can also trigger endoplasmic reticulum (ER) stress, decreased nitric oxide bioavailability and produce peroxynitrite (ONOO-), a very powerful radical, which contributing to cellular dysfunction and apoptosis
The authors used four different concentrations of 1.6, 4, 8, and 16 mg/kg and compared the results with the clinically approved drugs sodium valproate
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