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Clinical trials involving positron emission tomography (PET) with translocator protein expressed by activated microglia (TSPO) have demonstrated that seizures, temporal lobe epilepsy, frontal lobe epilepsy, and focal cortical dysplasia are associated with neuroinflammation, and their acute onset leads to chronic neuroinflammation and exacerbates its deterioration (145)

However, the long-term systemic effects on salivary glands are likely similar regardless of administration route

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Each batch of lyophilized peptide may have slight concentration variations due to manufacturing tolerances, meaning identical volumes from different batches deliver different actual doses

-10.9% lean body mass over 72 weeks) per the SURMOUNT-1 body-composition substudy [12]