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GLP-1 agonists carry a boxed warning based on rodent studies of thyroid C-cell tumors, and they are contraindicated in people with a personal or family history of medullary thyroid carcinoma or MEN 2 syndrome

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Increased government focus on metabolic disease management and strategic investment by global pharma companies are accelerating product launches and adoption across the region

Frequency: Once daily or every other day exposure maintains signaling without receptor desensitization

doi: 10.1016/j.jacc.2005.09.068 114 ChangWZhuFZhengHZhouZMiaoPZhaoLet al