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Influence of Abdominal Pressure on Respiratory and Abdominal Organ Function

Experimental studies suggest that activation of these pathways may influence appetite-related signaling, food intake regulation, gastric physiology, and metabolic homeostasis

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Mancke etal, 2016

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qRT-PCR analysis revealed the marked upregulation of CDKN2A (encoding p16) , CDKN1A (encoding p21) , interleukin-8 ( IL-8) , and matrix metalloproteinase ( MMP)-12 expression (Figure 1D)