Utzinger J, Keiser J, Shuhua X, Tanner M, Singer BH (2003) Combination chemotherapy of schistosomiasis in laboratory studies and clinical trials
Given its favorable performance in related conditions, favorable side-effect profile, and low cost, it is expected to become an important option for HAPH treatment
The research protocol and all methods and procedures used in the study were performed in accordance with the research and animal handling guidelines and regulations of King Khalid University (Abha, KSA) and AVMA Guidelines for the Euthanasia of Animals to ensure that this study will accomplish and follow ethical practices and guidelines about welfare and treatment of animals connected with this research
Clinically, no specific preventive drugs exist
Therefore, patients taking allopurinol and febuxostat treat GA through synergism: reducing FA levels to suppress inflammatory responses and inhibiting xanthine oxidase to lower uric acid levels
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