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Currently, there is an ongoing randomised double-masked placebo-controlled trial, the SUMMIT trial, studying the efficacy and safety of tirzepatide, a dual agonist of glucose-dependent insulinotropic polypeptide and GLP-1 receptors, versus placebo in HFpEF patients with obesity (NCT04847557)

The medications remain covered for conditions like diabetes and heart disease but not for obesity itself

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Benefits for Men While PT-141 is not officially FDA-approved for men, it is widely used off-label to address erectile dysfunction (ED) and low libido

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