Bacterial cultures, or an equivalent volume of 10% (v/v) FBS-HI in Brucella broth (mock infection control), were diluted in co-culture medium (DMEM or RPMI 1640 supplemented with 10% (v/v) Brucella broth and 5% (v/v) FBS-HI) to achieve an MOI of 35 or 50
The stomach was opened along the greater curvature
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Marc Dunoyer, the companys rare disease head, in a statement called Ultomiris a transformative treatment option for NMOSD, with the potential to eliminate relapses with a convenient dosing schedule every eight weeks. The approval was backed by data from a Phase III trial that met its primary efficacy endpoint, preventing relapse in all 58 treated patients over a median of 73.5 weeks, compared to 20 relapses in the placebo arm of a trial for AstraZenecas other NMOSD therapy Soliris