At 10 mg/ml, twenty units would be 2 mg, a potentially dangerous amount for someone in early dose escalation
Box 1: Recent Trump Administration Obesity Drug Initiatives In November 2025, the Trump administration announced reaching a deal with Eli Lilly and Novo Nordisk to lower the cost of their GLP-1s for Medicare, Medicaid, and those purchasing the drugs directly from the manufacturers through a new TrumpRx website
Price ranges above reflect self-pay, cash-pay pricing
Noel AA, Koch AR, Engel LS
Tirzepatide works on two hormones (GLP-1 and GIP) Retatrutide works on three hormones (GLP-1, GIP, and glucagon) This is why discussions around tirzepatide vs retatrutide often focus on whether triple-action therapy may provide enhanced results
They are not required to demonstrate efficacy, and they do not need to prove that their delivery method works as claimed before reaching the market