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When administering a higher dose, the benefits should be weighed against the risks

Instead, reducing high-impact activities like running while maintaining low-impact exercise such as swimming or cycling provides the best balance

Rescue therapy was needed by 8%, 25%, and 67%, respectively. Five milligrams preserved most, but not all, of the benefit of continuing the effective dose

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This can help prevent future occurrences and may be important for legal or medical follow-ups