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Moreover, excessive APAP increases hepatic CXCL16 levels, CXCL16 deficiency significantly reduces the production of pro-inflammatory cytokines TNF- and IL-6, and inhibits neutrophils migration to the site of injury, other chemokines CXCL1 and CXCL2 expression are also diminished, suggesting that CXCL16 may be involved in neutrophil infiltration in APAP hepatotoxicity [38]

All medicines should be kept out of the reach of children

The standard 500 mcg oral dose of the arginate form may deliver comparable systemic exposure to much higher doses of the acetate form taken orally

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