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Kelly Dineley) and Animal Resource Center at UTMB for the resources provided for the animal studies

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5-Amino-1MQ is a substrate-mimetic inhibitor that occupies the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)

Starting too high leads to severe GI side effects

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