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The patient initially presented symptoms at 1.5 years of age, with intermittent knee arthralgia
Do these symptoms remind you of anything
The short answer is yes
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Since VTA GABA neurons in the VTA have also been shown to be outwardly projecting, it is also possible that GLP-1Rs are expressed on GABA neurons in the VTA that project to downstream nuclei including the NAc, CeA, prefrontal cortex, lateral hypothalamus, and the lateral habenula 68,69,70
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