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Outside of that group, published safety data is essentially absent

10 Given the high prevalence of obesity and metabolic syndrome in patients with HS as well as the anti-inflammatory effects of GLP-1 RAs, these agents may offer therapeutic benefits in HS

Additional Phase 3 trials are still underway, including TRIUMPH-2 (evaluating retatrutide in adults with obesity and type 2 diabetes) and TRIUMPH-3 (evaluating cardiovascular outcomes), with results expected later in 2026

Determining the effects of glutathione on ulcerative colitis will require more research in humans

Stick to gentle exfoliation 2-3 times per week maximum

The drug is metabolized primarily through proteolytic cleavage and does not undergo hepatobiliary excretion as an intact molecule