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People with low B12 may experience: Persistent fatigue or low energy Weakness Brain fog, concentration issues, or memory changes Low mood or irritability Pins and needles, numbness, or nerve-type sensations Mouth ulcers or a sore tongue Paleness or shortness of breath (if anaemia is present) Some symptoms can become more serious if deficiency is prolonged, particularly neurological symptoms
Wang L, Liu Y, Du T, Yang H, Lei L, Guo M, et al
4 Vitamin B12 and 1-carbon (1 C) metabolism markers during in vivo reprogramming
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MEK inhibitors markedly reduced tumor growth in high-MAP3K8 PDX models, compared with low-MAP3K8 PDX models
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