With an oral supplement, the B12 needs to be absorbed through your digestive system first before getting to your blood, which takes a lot longer
Vigorous shaking can denature the peptide, meaning it can break the fragile bonds that give the molecule its specific shape and function
If your levels were very low, this early phase can feel especially noticeable
Most of the product licences, or marketing authorities as they are called in the UK, for hydroxocobalamin date from the 1990s when the requirement for evidence was different than it is now
Volume and ratio depend on peptide stability and study requirements
Energy support should feel personal, practical, and realistic