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Levey, A
Specifically, hypoxia-induced glycolysis in PDAC cells provokes the lactylation of lysine 34 on NUSAP1, a spindle microtubule regulator, which enhances its expression by hindering its degradation, consequently establishing an NUSAP1-LDHA-glycolysis-lactate feedforward loop and facilitating metastasis in PDAC
in particular, the specific association between donor microbiota composition and ENS restoration in patients with DGE requires clarification
SU, sulfonylurea
It is not proven in human RCTs at the body-composition level
10.1038/s41586-018-0650-9 Nature 150 ReynaudC.BaasD.GleyzalC.Le GuellecD.SommerP
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