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Laugh lines are caused by the repetitive motion of smiling

It is also known that oral contraceptives may lower pyridoxine levels in some individuals, which could be considered a drug-nutrient interaction of clinical relevance

Inflammatory bowel disease (IBD) is inflammation of the intestinal tract and causes the inability of the intestinal tract to absorb nutrients

1 Deficiency is often due to a lack of B12 foods in the diet, absorption issues, and/or genetic mutations that affect uptake

A smaller group feels briefly worse first: tired, achy, headachy or off-colour for a day or two

That is why we use B12 as a supporting piece of a full medical weight loss program, not a standalone fix