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NHS and NICE-recommended weight management approaches including structured lifestyle interventions, behavioural support, and where appropriate, licensed pharmacological treatments such as orlistat or GLP-1 receptor agonists have a substantially stronger evidence base than L-carnitine supplements
Further analysis looked at whether a greater weight loss led to even more benefits, but results showed that the benefits were seen regardless of starting weight or how much weight participants lost
Researchers repeatedly identify reduced intake as a major reason nutritional side effects may develop during GLP-1 therapy
Moderate green tea consumption was not associated with increased risk of kidney stone formation (24) , but the caffeinated form may cause insomnia and nausea
Other reported symptoms Sources: Phase 3 TRIUMPH-4 trial and Phase 2 NEJM trial Dysesthesia, or a change in skin sensation, was a new finding in the Phase 3 trial