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6 KPV / -MSH (PubMed)KPV tripeptide (Lys-Pro-Val), the C-terminal of -MSH, and anti-inflammatory NF-B signalling

Therefore both GST and efflux pumps overexpression may confer high levels of resistance to the cytotoxic action of several antineoplastic drugs

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A 2025 study published in Biogerontology demonstrated dose-dependent telomere length extension in normal human cells through upregulation of hTERT (the telomerase catalytic subunit) and telomerase enzyme activity meaning Epithalon appears to reactivate the cellular machinery that maintains telomere length rather than just slowing its shortening