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In type 2 diabetes, a deterioration of insulin secretion and the development of peripheral insulin resistance lead to the development of hyperglycaemia
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One analysis of multiple studies suggests that folic acid supplements can reduce the risk of stroke in people who have not already suffered a stroke, but they do not reduce the risk of second stroke in people who have already had one
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Second, reduced food intake means less food in the stomach to buffer absorption
Its stated concern is functional rather than metabolic: both drugs touch gastrointestinal motility and nausea, so any overlap shows up as symptoms
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