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[12] [13] Whether retatrutide will carry a similar or different pattern of cold-related symptoms will only become clear once Phase 3 trial data and regulatory review are complete

To date, large-scale studies in humans have not shown a clear, direct link between these medications and an increased risk of MTC

N Engl J Med 2016;375:183444.ArticlePubMed 36

Mechanism of action What sets retatrutide apart is its ability to simultaneously activate three key receptors: the glucose-dependent insulinotropic polypeptide (GIP) receptor, the glucagon-like peptide-1 (GLP-1) receptor, and the glucagon (GCG) receptor

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