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MHT isnt a nothing drug, and touting it as the fountain of youth and longevity is irresponsible, even though reducing the risk of osteoporosis is a huge long-term health benefit

Jang HH et al

Additionally, these substances depleted ATP levels, impaired mitochondrial function, reduced cell proliferation, and induced autophagy, necrosis, and apoptosis 50

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GLP-1 agents, while costly and not yet guideline-endorsed for prevention, offer broader metabolic benefits without inherent bleeding risk