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Injectable Peptides Most peptides are poorly absorbed when taken orally because digestive enzymes and stomach acid break them down before they can reach the bloodstream

Oral glutathione is largely broken down by stomach acids, resulting in poor absorption

Second, up-titration regimens for GLP-1 analogs have mitigated adverse GI side effects, reducing their prevalence and severity in both clinical trials and post-marketing surveillance (327)

Competing interests The authors have no relevant financial or non-financial interests to disclose