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Phase 3 TRIUMPH-4 showed 28.7% weight loss at 68 weeks, substantially exceeding CagriSema's 20.4% at 68 weeks

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Notable is the composition of the weight loss: fat-mass reduction was roughly three times greater than the reduction in lean mass (33.9 percent versus 10.9 percent)

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C.CariouB.PiletiM.RoseL.AxelsenM.et al (2017)