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Indeed there are some studies showing these outcomes in humans (PMIDs: 30681787 & 34491424) Collagen contains a high proportion of glycine (33%), proline (~10%), & hydroxyproline (~10%) which may provide substrate for connective tissue synthesis However, one of the best protein metabolism labs in the world has conducted 2 studies demonstrating that collagen & collagen peptide supplementation does NOT increase connective tissue synthesis (PMID: 39086044 & 37202878)

A warm thank you to all co-authors and collaborators, Asger Bihlet, Yves Henrotin, Francois Rieger, Olivier Godeaux, MD, MPH, Helene Rovsin, Peter Alexandersen, Edith Min Chu Lou for their dedication throughout this demanding but essential process

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The solution might be to change the medication or add B12 supplements

The unit calculations produce clean, round numbers at the most common doses

If CagriSema truly prevents the metabolic slowdown associated with weight loss, as the preclinical data suggests, it could produce more durable outcomes with less weight regain after treatment completion