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Half-maximal inhibitory concentration (IC50) of Metformin and Simvastatin In our previous study, we found that metformin exhibited inhibitory effects on glioblastoma proliferation both in vitro and in vivo

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Specifically, INF- released by CD8 + T cells downregulated the expression of SLC7A11 and SLC3A2, leading to a decrease in GSH and an increase in lipid peroxidation

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