In recent years, natural polyphenols have shown great potential in combating cisplatin ototoxicity due to their powerful antioxidant, anti-inflammatory and anti-apoptotic properties.A variety of polyphenolic compounds, such as resveratrol, curcumin, quercetin, etc., can effectively attenuate the damage of cisplatin on Corti organs, spiral ganglion neurons and vascular striatum by scavenging free radicals, inhibiting the release of inflammatory factors, and regulating the expression of apoptosis-related proteins
den Abeelen AS, Lagro J, van Beek AH, Claassen JA
Since BPC-157s discovery in the early 1990s, the medical community has learned a lot about it
GPx3 upregulated in clear-cell ovarian cancer may promote chemotherapeutic resistance (94)
Although formal dosage guidelines have yet to be established, clinical studies offer useful insight into the safe and effective handling of BPC-157 and other research peptides
Considering that highly sensitive xCT inhibitors and cystine deprivation can induce ferroptosis, several ferroptosis-inducing agents have been developed [15,35,42]