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Sinclair A, Xie X, Teltscher M, Dendukuri N
Signs might include itching, hives, or difficulty breathing
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Medical directors need to review protocols, especially if a patient doesn't respond after 4-6 weeks, side effects appear, or new regulations come up
It requires a needle, which may lead to anxiety or discomfort, especially for individuals with a fear of needles
At a normal therapeutic dose, acetaminophen is primarily metabolized by the liver to sulfate and glucuronide conjugates, while a SMALL amount is metabolized by CYP2E1 to a highly reactive intermediate, N-acetyl-p-benzoquinone imine (NAPQI)
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