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EP2890390Treatment of Osteoarthritis WITH Incretin Hormones or Analogues Thereof (2014)
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Most gastrointestinal AEs reported were non-serious (99.5% of AEs) and mild-to-moderate (98.1%) in severity, which did not necessitate dose reduction or discontinuation." In other words, serious side effects are very rare, and the typical patient experiences side effects early on that taper off with time
Patients with diabetes taking insulin or sulfonylureas should monitor blood glucose closely when starting ispaghula, as dose adjustments may be needed
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