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This makes the drug a treatment that could well be applied much more broadly to the expanding population of patients with overweight and obesity and cardiovascular disease. Commenting for TCTMD, Cynthia Jackevicius, PharmD (Western University of Health Sciences, Pomona, California), said the findings, published simultaneously online in the New England Journal of Medicine , confirm what we really thought might happen, but its so important to see it in a cardiovascular outcomes trial. The magnitude of the absolute MACE reduction translates into a number needed to treat of 67, which is a pretty good number, she said

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